Jesse was betrayed by Walt to Jack, who, at Todd Alquist's request, took Jesse as a slave to cook meth for him and his gang. Walt pleaded with Jack, but could not stop him, and, following a large shootout, Steve was killed and Hank was executed. At the last minute, though, Jack Welker and his gang appeared, Walt having just minutes before called them to come save him from Jesse, who Walt had thought was alone and about to kill him. Jesse put Walt into a trap when he falsely threatened to burn his accumulated fortune, and Hank and Gomez finally arrested Walt. Later, upon learning a devastating revelation from Saul Goodman, Jesse betrayed Walt by teaming up with Hank Schrader, Walt's DEA brother-in-law who had become aware of Walt's criminal activities, and his longtime DEA partner Steve Gomez, to bring Walt down.
Mike convinces a local distributor to buy out their shares of the stolen methylamine, and after some compromises on Walt’s behalf, Jesse was free to leave the business. When the train robbery results in the death of an innocent child, Jesse decides to pull out of the meth business permanently. He often attended Narcotics Anonymous meetings to help deal with these feelings. While Walt had developed into a ruthless drug lord motivated largely by vanity, ego, and greed, Jesse was horrified at the brutality of the drug trade, and often expressed strong feelings of guilt about the deaths of people he'd been associated with, especially the deaths of his girlfriend Jane Margolis and chemist Gale Boetticher, the latter Jesse reluctantly killed himself. Following multiple tense, deadly partnerships with distributors Tuco Salamanca and Gustavo Fring that ended in their respective deaths, however, and with the help of Jesse, Gus's former enforcer Mike Ehrmantraut, and Lydia Rodarte-Quayle, Walt eventually became the head of his own drug empire: the largest methamphetamine manufacturing operation in US history, branching as far as Eastern Europe.
At the beginning of his new career, he and Walt made mere thousands of dollars through street dealing, and were constantly met with failure. Jesse began his partnership with Walt in 2008, manufacturing chemically pure meth out of an RV in the deserts of New Mexico. Jesse operated under the pseudonym "Cap'n Cook", adding chili powder to make his methamphetamine stand out in the market. In the 2000s, Jesse partnered with Emilio Koyama to manufacture meth. Jesse was horrified by the brutality at the higher levels of the drug trade, which ultimately resulted in his decision to leave the criminal business. Although Jesse and Walt began as amateur, small-time meth cooks, they soon climbed up the drug hierarchy.
Jesse began his criminal career as a low-level distributor before working with Walt. He is a retired career criminal, and was the partner of his former chemistry teacher Walter White in the the Albuquerque methamphetamine drug trade as a manufacturer & distributor, and also fronted a meth distribution chain with his friends. Jesse Bruce Pinkman is a citizen of Alaska and friend of Skinny Pete and Badger. ― Jesse condemning his group and himself You're nothing to me but customers! I made you my bitch! You okay with that? Huh? You accept? So, no matter what I do, hooray for me because I'm a great guy? It's all good? No matter how many dogs I kill, I just what, do an inventory and accept? I mean, you backed your truck over your own kid and you, like, accept? What a load of crap! No, y-you know what? Why I'm here in the first place? Is to sell you meth.